The current lifestyle and bad eating habits have caused various chronic and refractory diseases, among them Diabetes mellitus, a metabolic disorder characterized by increased blood glucose level that causes the alteration of carbohydrates, fats and proteins as a result of an absolute or relative lack of insulin (WHO, 1999). According to pathogenesis, Diabetes mellitus is divided into type 1 and type 2 diabetes. Today, we have some medications used to control these symptoms, but their efficacy is limited and they often have side effects, including increased appetite and weight gain. For this reason, in recent years, Artemisia annua and its molecule artemisinin have been the object of study (clinical phase II studies in progress), being able to highlight its possible effectiveness on Diabetes mellitus as well as in improving liver and kidney functions.