Malaria is one of the leading causes of death worldwide. Malaria is an infectious disease which is endemic in 109 countries, caused by protozoan parasites of the Plasmodium genus, transmitted by mosquitoes. It affects primarily sub-saharan Africa. Every year, 200 million are infected and more than 400.000 people die from malaria. Since 2012, the WHO recommends using Artemisinin Combination Therapy (ACT).


Fever, also known as pyrexia and febrile response is defined as having a temperature above the normal range due to an increase in the body’s temperature set-point. Fever can be caused by many medical conditions ranging from non-serious to life-threatening, including viral, bacterial and parasitic infections such as the common cold, urinary tract infections, meningitis, malaria and appendicitis among others. Artemisinin has been used for centuries in Chinese medicine to treat the fevers associated with malaria, and now completed clinical trials confirm its efficacy in such cases.