Leishmaniosis

leishmaniosis artemisia annua

Artemisinin, a sesquiterpene present in the Artemisia annua plant, emerges as a promising adjuvant in the leishmaniasis treatment.

leishmaniosis artemisia annua

The current challenges of leishmaniosis

Leishmaniosis is a disease with high mortality and morbidity caused by intracellular protozoa of the genus Leishmania, transmitted by the bite of certain types of sandflies. It mainly affects dogs, but can also affect humans and cats. The clinical manifestations of the disease range from skin ulcers to fatal inflammation of the liver and spleen. Being a chronic disease, most treatments for this disease become toxic, expensive or ineffective.

The role of artemisinin in leishmaniosis

Sesquiterpenes, such as artemisinin, are a class of biomolecules present in plants with proven antimicrobial and antiparasitic activities. Multiple international scientific publications have demonstrated the great potential of artemisinin present in the leaf of the medicinal plant Artemisia annua as a coadjuvant for the treatment of parasites.